Arterial Calcification and Calcium Antagonists

Arterial calcification and calcium antagonists: what does it mean?

Since their introduction more than 30 years ago, calcium antagonists have emerged as one of the most attractive and widely used classes of antihypertensive agents. Of the 20 to 25 million patients receiving medication for hypertension in the United States, about one quarter are taking calcium antagonists. The wide appeal of the calcium antagonists is attributable to several features, including ...

Atherosclerosis, calcium, and calcium antagonists.

Medial Arterial Calcification

Peripheral arterial disease (PAD) refers to occlusion or narrowing of the upper and lower extremity arteries, causing insufficient blood flow to the limbs. Patients with PAD often present with symptoms, such as claudication, ischemic rest pain, ischemic ulcerations, and limb loss. These patients are also highly predisposed to cardiovascular morbidity and mortality. PAD is underdiagnosed, and li...

Breast Arterial Calcification

Circulation. 2017;135:499–501. DOI: 10.1161/CIRCULATIONAHA.116.025277 February 7, 2017 499 Tamar S. Polonsky, MD, MSCI Philip Greenland, MD A large proportion of cardiovascular events occur among women whose 10year estimated atherosclerotic cardiovascular disease risk is <7.5%, and thus guidelines would not routinely recommend statins for such patients before their events.1 Additional strategie...

Clinical pharmacology of calcium antagonists. Satellite symposium on calcium antagonists.

A new class of agents has been made available for the treatment of hypertension. These calcium antagonists have rapid bioavailability and dramatic antihypertensive effects through reduction of total peripheral resistance and the vascular resistance of the major target organs of the body. These changes are usually associated with unchanged cardiac output, preserved organ blood flows, maintained ...